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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLTK
All Species:
21.21
Human Site:
Y681
Identified Species:
46.67
UniProt:
Q9NYL2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYL2
NP_057737.2
800
91181
Y681
S
D
R
S
R
N
K
Y
G
R
G
S
I
S
L
Chimpanzee
Pan troglodytes
XP_001146659
1107
121909
L995
R
P
K
T
L
E
F
L
P
R
P
R
P
S
A
Rhesus Macaque
Macaca mulatta
XP_001086798
876
99398
Y757
S
D
R
S
R
N
K
Y
G
R
G
S
I
S
L
Dog
Lupus familis
XP_535966
800
91753
Y681
S
G
R
S
K
N
K
Y
D
R
G
S
V
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESL4
802
91701
Y681
S
D
R
S
R
N
K
Y
Y
R
G
S
V
S
L
Rat
Rattus norvegicus
XP_001059755
802
91679
Y681
S
D
R
S
R
N
K
Y
Y
R
G
S
V
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514764
800
91243
Y681
L
G
R
S
K
N
K
Y
C
R
G
R
G
S
L
Chicken
Gallus gallus
XP_421996
791
89577
R672
D
T
A
S
E
R
D
R
S
T
G
K
A
R
N
Frog
Xenopus laevis
Q7T2V3
1005
111856
R868
P
E
P
S
P
F
P
R
L
P
D
P
H
F
V
Zebra Danio
Brachydanio rerio
XP_687660
789
89601
Y678
H
N
Y
N
K
K
P
Y
Y
D
H
H
T
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95UN8
1161
128942
I1023
Y
H
M
Q
E
N
S
I
L
N
T
R
R
M
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.7
90.1
92
N.A.
91.7
91.4
N.A.
82.7
75.5
20
60
N.A.
21.3
N.A.
N.A.
N.A.
Protein Similarity:
100
35.7
90.8
94.7
N.A.
95.6
94.8
N.A.
90.1
83.7
34.6
74.5
N.A.
35
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
73.3
N.A.
86.6
86.6
N.A.
60
13.3
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
86.6
N.A.
93.3
93.3
N.A.
66.6
13.3
20
26.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
10
37
0
0
0
0
10
0
10
10
10
0
0
0
0
% D
% Glu:
0
10
0
0
19
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
0
0
10
0
% F
% Gly:
0
19
0
0
0
0
0
0
19
0
64
0
10
0
0
% G
% His:
10
10
0
0
0
0
0
0
0
0
10
10
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
19
0
0
% I
% Lys:
0
0
10
0
28
10
55
0
0
0
0
10
0
0
10
% K
% Leu:
10
0
0
0
10
0
0
10
19
0
0
0
0
10
55
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
10
0
64
0
0
0
10
0
0
0
0
10
% N
% Pro:
10
10
10
0
10
0
19
0
10
10
10
10
10
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
55
0
37
10
0
19
0
64
0
28
10
10
0
% R
% Ser:
46
0
0
73
0
0
10
0
10
0
0
46
0
64
0
% S
% Thr:
0
10
0
10
0
0
0
0
0
10
10
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
64
28
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _